Publications

2024

Chitra Togra, Riya Dhage, Purusharth I Rajyaguru, Tdh3 and Rom2 are functional modulators of a conserved condensate-resident RNA-binding protein, Scd6, in Saccharomyces cerevisiae, Genetics, (2024);, iyae127, https://doi.org/10.1093/genetics/iyae127

Roy, R., Das, G., Kuttanda, I.A. et al. Low complexity RGG-motif sequence is required for Processing body (P-body) disassembly. Nat Commun 13, 2077 (2022). https://doi.org/10.1038/s41467-022-29715-5
Roy, R. et al. Assay to Study the Phase-transition Behavior of Edc3, a Conserved Processing Body (P-body) Marker Protein. Bio-protocol 2022. https://doi.org/10.21769/BioProto .4487
Garg, M., Roy, D. et al. Low complexity RGG-motif containing proteins Scd6 and Psp2 act as suppressors of Cathrin heavy chain deficiency. BBA-MCR 2022. https://doi.org/10.1016/j.bbamcr.2022.119327

Parbin, S, Damodharan, S, Rajyaguru, PI. Arginine methylation and cytoplasmic mRNA fate: An exciting new partnership. Yeast. 2021; 38: 441– 452. https://doi.org/10.1002/yea.3653
Mohanan, G., Das, A., & Rajyaguru, P. I. (2021). Genotoxic stress response: What is the role of cytoplasmic mRNA fate? BioEssays, 43, e2000311. https://doi.org/10.1002/bies.202000311
Gopalakrishna Poornima, Gaurav Srivastava, Brinta Roy, Ishwarya Achappa Kuttanda, Iladeiti Kurbah & Purusharth I. Rajyaguru (2021) RGG-motif containing mRNA export factor Gbp2 acts as a translation repressor, RNA Biology, 18:12, 2342-2353, https://doi.org/10.1080/15476286.2021.1910403
Bhatter, N., Iyyappan, R., Mohanan, G., & Rajyaguru, P. I. (2021). Exploring the role of RRM domains and conserved aromatic residues in RGG motif of eIF4G-binding translation repressor protein Sbp1. Wellcome open research, 3, 102. https://doi.org/10.12688/wellcomeopenres.14709.3

Garg, M., Poornima, G., & Rajyaguru, P. I. (2020). Elucidation of the RNA-granule inducing sodium azide stress response through transcriptome analysis. Genomics, 112(5), 2978–2989. https://doi.org/10.1016/j.ygeno.2020.05.001
Sabnam Parbin, Gayatri Mohanan, Shirish Gole, Devika Joshi, Monmita Bhar, Purusharth I. Rajyaguru, DEKTV and YVG motifs in the Lsm domain are important for the activity of Scd6, a conserved translation repressor protein, Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, Volume 1863, Issue 2, 2020, 194474, ISSN 1874-9399, https://doi.org/10.1016/j.bbagrm.2019.194474
If you are a teacher or aspire to be one then you may find this article useful. Here Raj has summarized his experiences as ‘new’ teacher at IISc. Raj is passionate about teaching and believes that learning to teach has taught him how to learn. https://www.ias.ac.in/listing/bibliography/reso/Purusharth_I_Rajyaguru

Bhatter, N., Roy, R., Shah, S., Sastry, S. P., Parbin, S., Iyappan, R., Kankaria, S., & Rajyaguru, P. I. (2019). Arginine methylation augments Sbp1 function in translation repression and decapping. The FEBS journal, 286(23), 4693–4708. https://doi.org/10.1111/febs.15057
Poornima G, Mythili R, Nag P, Parbin S, Verma PK, Hussain T, Rajyaguru PI (2019): RGG-motif self-association regulates eIF4G-binding translation repressor protein Scd6. RNA Biol. 2019 Jun 12:1-13. https://doi.org/10.1080/15476286.2019.1621623

Roy R, Rajyaguru PI (2018): Stress Granules and P-Bodies: An Insight into mRNA Translational Control and Decay. Proc Indian Natn Sci Acad 84 No. 2 June 2018 pp. 479-491; https://api.semanticscholar.org/CorpusID:56442054
Roy D, Rajyaguru PI (2018): Suppressor of clathrin deficiency (Scd6)-An emerging RGG-motif translation repressor. Wiley Interdiscip Rev RNA. 2018 May 22:e1479. https://doi.org/10.1002/wrna.1479

Poornima G, Shah S, Vignesh V, Parker R, Rajyaguru PI (2016): Arginine methylation promotes translation repression activity of eIF4G-binding protein, Scd6. Nucleic Acids Res. 2016 Nov 2;44(19):9358-9368. Epub 2016 Sep 8; https://doi.org/10.1093/nar/gkw762